Executive Medical Director, Global Clinical Lead

JobsCloseBy Editorial Insights

Merck Group is seeking an Executive Medical Director, Global Clinical Lead to provide strategic, senior medical leadership for global immunology development programs, shaping indication strategy, target product profiles, and evidence-generation plans while ensuring scientific rigor and patient-centricity across Regulatory, Safety, Biostatistics, Translational Medicine and Medical Affairs. The role requires an MD or international equivalent, 10+ years in immunology and 5+ years of medical leadership in pharma, with proven global Phase 2/3 leadership and regulatory interactions; on-site at least 3 days a week in Eysins, frequent travel. To optimize your application, tailor your CV to highlight global program leadership, benefit-risk decision making, protocol development, successful regulatory engagements, and concrete milestones, with a concise cover letter linking your track record to asset strategy and patient outcomes; demonstrate collaboration across functions and readiness to thrive in a diverse, inclusive culture.

Work Your Magic with us!  

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

Your Role

You will provide senior medical and strategic leadership across global immunology clinical development programs, ensuring scientific rigor, patient-centricity, and alignment with asset strategy, portfolio priorities, and regulatory expectations. You will lead global clinical development planning, including target product profiles, indication strategy, evidence generation plans, and lifecycle considerations.

You will serve as a senior medical decision-maker within global program teams, providing strategic recommendations on development options, benefit-risk considerations, data interpretation, and key program risks. You will drive protocol development, oversee clinical execution, and ensure decisions are clearly documented with rationale, risks, and mitigations.

You will collaborate closely across Clinical Development, Regulatory, Safety, Biostatistics, Translational Medicine, Medical Affairs, Market Access, and other key functions to ensure integrated delivery of global development plans. You will support and lead, as appropriate, regulatory interactions and communicate clinical results through study reports, regulatory documents, publications, governance forums, and external scientific forums.

You will engage investigators, key opinion leaders, advisory boards, and patient communities compliantly to inform clinical strategy and enhance scientific credibility. You will provide matrix leadership to cross-functional teams and mentor clinical development colleagues as needed, fostering accountability, collaboration, and high-quality execution. This role will be based for a minimum of 3 days a week onsite.

Who You Are

• Medical Degree, such as MD, DO, or international equivalent, required; board certification preferred
• 10+ years of experience in immunology, rheumatology, or related autoimmune/inflammatory diseases, with hands-on patient care experience
• 5+ years of medical leadership experience within pharma/biotech clinical development
• Prior experience as a Global Clinical Lead, Clinical Program Lead, or equivalent for complex clinical development programs
• Demonstrated experience developing clinical development plans and leading global Phase 2/3 or registrational studies
• Strong understanding of benefit-risk assessment, indication strategy, evidence generation, and lifecycle planning
• Proven ability to lead global clinical trials and cross-functional teams in a complex matrix environment
• Experience supporting or leading health authority interactions, including FDA, EMA, or other major regulatory agencies
• Strong GCP/ICH knowledge and understanding of global regulatory requirements
• Ability to influence senior stakeholders, communicate strategic recommendations clearly, and represent clinical strategy in governance forums
• Excellent cross-functional leadership, communication, and decision-making skills
• Track record of delivering milestones under tight timelines while maintaining quality and scientific integrity
• Willingness to travel domestically and internationally as needed

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!