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PSI seeks a Postdoctoral Fellow in cancer radioligand therapy to design and conduct in vitro and mouse model studies, explore tumor biology and microenvironment interactions, and report findings to advance clinical translation in an interdisciplinary team. A PhD in radioligand therapy, cancer therapeutics, or tumor biology is required, with hands-on cancer mouse model experience (prostate models a bonus) and a willingness to work with radionuclides; strong English communication is essential. The two-year on-site position in Villigen offers structured on the job training and career development. Apply by March 1, 2026 online with publications and referees; tailor your CV and cover letter to emphasize relevant radiopharmaceutical work and translational impact, and contact Dr Michal Grzmil with questions.

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Postdoctoral Fellow in cancer radioligand therapy

The Paul Scherrer Institute PSI is the largest research institute for natural and engineering sciences within Switzerland. We perform cutting-edge research in the fields of future technologies, energy and climate, health innovation and fundamentals of nature. By performing fundamental and applied research, we work on sustainable solutions for major challenges facing society, science and economy. PSI is committed to the training of future generations. Therefore, about one quarter of our staff are post-docs, post-graduates or apprentices. Altogether, PSI employs 2300 people. 
The Pharmacology Group at PSI advances targeted radionuclide therapy to address unmet biomedical needs, with a particular focus on the treatment of malignant cancers. For more information, please visit our website.
For the Center for Radiopharmaceutical Sciences, we are looking for a

Your tasks

• Design and conduct radioligand therapy studies in vitro and in cancer mouse models to preclinically develop safe and efficacious innovative cancer treatment 
• Investigate tumor biology and tumor–microenvironment interactions, including target expression, tumor heterogeneity, treatment response, and resistance mechanisms, to support rational therapy development and optimization 
• Work in an interdisciplinary environment, collaborating closely with research partners and supporting the team with data and scientific expertise 
• Analyze and report experimental results through scientific presentations and publications with a focus on clinical translation

Your profile

• PhD degree in radioligand therapy, cancer therapeutics, tumor biology or a related field 
• Experience in cancer mouse models - prostate cancer model is an advantage 
• Willingness to work with radionuclides and mouse models is essential 
• Knowledge of drug screens, omics technologies (e.g., Proteomics) is a plus 
• Strong motivation, excellent communication and presentation skills in English

We offer
Our institution is based on an interdisciplinary, innovative and dynamic collaboration. You will profit from a systematic training on the job, in addition to personal development possibilities and our pronounced vocational training culture. If you wish to optimally combine work and family life or other personal interests, we are able to support you with our modern employment conditions and the on-site infrastructure. 
Your employment contract is limited to 2 years.
For further information, please contact Dr Michal Grzmil, e-mail ([email protected]).
Please submit your application online by 1 March 2026 (including list of publications and addresses of referees) for the position as a Postdoctoral Fellow (Index-Nr. 2222-26166).
Paul Scherrer Institute, Human Resources Management, Pascale Bärtschi,  5232 Villigen PSI, Switzerland
www.psi.ch