Research Technician II - Cancer Cell Therapy

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BCM seeks a Research Technician II to support translational immunotherapy research focused on developing T cell therapies for cancer, with emphasis on pediatric patients and a Phase I/II CAR T trial, within the Center for Cell and Gene Therapy and its Houston partners. This full‑time, on‑site role covers cell culture, transduction, flow cytometry, ELISpot/ELISA, RNA sequencing, basic cloning, and careful electronic lab notebook documentation, with limited animal work (<10%). Minimum: bachelor’s in a basic science (four years may substitute); master’s preferred for flow and cell culture. Visa sponsorship is not available; applicants must be authorized to work in the U.S. To apply, tailor your resume to demonstrate clinical trial support, collaboration, data presentation, and readiness to contribute across labs and weekly seminars.

Summary

The position will support ongoing immunotherapy research with the goal of developing novel T cell therapies for cancer with a focus on cancer in children. The position includes a translational research component that supports the development of new therapies and a clinical research element supporting a Phase I/II clinical trial of CAR T cells for cancer patients. The position will also be integrated within the larger Center for Cell and Gene Therapy which is a highly collaborative translational research center affiliated with Texas Children’s Hospital, Baylor College of Medicine and Houston Methodist Hospital. Attendance at weekly educational seminars/lab meetings during standard work hours is generally expected. 

Job Duties

• Conducts and analyzes validation experiments to support Phase I/II clinical cell therapy trials for cancer.
• Conducts experiments to analyze cell and tissue samples of patients treated on Phase I/II clinical trials.
• Conducts and analyzes experiments in the translational laboratory to develop novel cell therapy products - Relevant techniques include cell culture, transduction, transfection, ELISpot, ELISA, nanostring/RNAseq, flow cytometry, miniprep/maxiprep, basic cloning procedures.
• Documents results of experiments in electronic lab notebooks.
• Documents results of validation experiments according to clinical laboratory specifications.
• Provides assistance with animal work (mice only, less than 10% of total effort).
• Prepares data for presentation and present data at scheduled laboratory meetings (Omer Lab, Rooney lab and optional CAGT wide lab presentations).
• Collaborates with and assists other laboratory members on their translational projects including post-doctoral fellows and graduate students.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• No experience required.

Preferred Qualifications

• Master's degree in a basic science or a related field.
• Flow cytometry experience.
• Cell culture experience.

Work Authorization Requirement:

This position is not eligible for visa sponsorship. Candidates must be legally authorized to work in the United States at the time of application and throughout the duration of employment. 

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.