Bioprocess Applications Engineer 3

JobsCloseBy Editorial Insights

Merck Group’s MilliporeSigma seeks a Bioprocess Applications Engineer 3 in Bedford, MA, onsite, full time, to join the Single Use and Integrated Systems Product Development team. You’ll blend engineering fundamentals with hands on experimentation, data analysis and modeling to evaluate next generation bioprocessing platforms, translate insights into product requirements, and guide development and customer success from concept to commercialization. Focus areas include CFD and mechanistic or data driven models of flow, mixing and heat transfer, designing application studies and scale down models, and cross functional collaboration with customers and internal teams. Qualifications: PhD in engineering or Master’s with 4+ years, or Bachelor’s with 5+ years; preferred: CFD, single use tech, DOE and strong communication. Apply on the company site with concrete examples of relevant work and a clear Bedford fit.

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Your Role:

We’re seeking a Bioprocess Applications Engineer 3 to join the Single Use and Integrated Systems Product Development team, part of MilliporeSigma’s Process Solutions business unit. Based at our Bedford, MA campus, this role will support the development and application of integrated platform solutions for next-generation bioprocessing.

In this role, you will combine engineering fundamentals, hands-on experimentation, data analysis, modeling, and customer-focused problem-solving to evaluate emerging technologies and characterize system performance. You will translate application insights into product requirements, technical recommendations, and practical guidance that support both product development and customer success.

This position is ideal for an engineer who enjoys applying technical depth to real-world bioprocessing challenges — defining the right problem, developing appropriate experimental or modeling approaches, and converting insights into recommendations that support product development and customer success.

Responsibilities:

• Apply engineering fundamentals and bioprocessing knowledge to characterize system performance and guide product development.
• Translate customer and process needs into clear technical questions, experimental plans, and decision-ready recommendations.
• Develop and apply CFD, mechanistic models, data-driven approaches, and other in silico tools, to evaluate flow, mixing, shear, pressure drop, heat transfer, residence time, mass transfer, and related performance characteristics.
• Design and execute application studies, test methods, and scale-down models under customer-relevant conditions.
• Translate application learnings into product requirements, technical recommendations, customer-facing materials, and practical guidance that support product adoption and successful use in bioprocessing workflows
• Collaborate with cross-functional teams, external partners, and customers to advance technologies from concept through commercialization.
• Support customer trials, investigations, and new use cases by communicating findings and capturing actionable feedback to inform future product and application development.

Who You Are:

Minimum Qualifications:

• Ph. D. in an Engineering field (e.g., Chemical Engineering, Mechanical Engineering, Biochemical Engineering, etc.)

-OR-

• Master’s Degree in an Engineering field (e.g., Chemical Engineering, Mechanical Engineering, Biochemical Engineering, etc.) with 4+ years of industry experience

-OR-

• Bachelor's Degree in an Engineering field (e.g., Chemical Engineering, Mechanical Engineering, Biochemical Engineering, etc.) with 5+ years of industry experience

Preferred Qualifications: 

• Strong foundation in fluid dynamics, transport phenomena, thermodynamics, and scale-up and scale-down principles.
• Hands-on experience applying CFD, Multiphysics simulation, mechanistic modeling, and other quantitative approaches to solve practical engineering problems.
• Experience developing experimental plans, scale-down models, test methods, or representative systems to characterize product or application performance.
• Experience with single-use technologies or bioprocessing workflows through product development, process development, manufacturing, or field applications.
• Strong data analysis skills, including experience with statistical analysis, mathematical modeling, coding, or visualization tools such as Python, MATLAB, R, JMP, Minitab, or similar platforms.
• Knowledge of product and process development practices, such as design of experiments, FMEA, design for manufacturing, test method development, qualification, or validation.
• Strong communication skills with the ability to interpret technical results and explain findings clearly to both technical and non-technical stakeholders.

Pay Range for this position - $84,900 - $127,300

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!