Principal Scientist I Crop Protection Research Chemistry (m/f/d)

Syngenta Group, a global leader in agricultural technology and innovation, is seeking a Principal Scientist I in Crop Protection Research Chemistry (m/f/d) to join its team at the R&D Center in Stein AG, Switzerland. This full-time, onsite role sits within a world-class crop protection chemistry group focused on designing and synthesizing novel bioactive ingredients that support healthy crops. The company employs roughly 60,000 people across more than 100 countries, working to deliver crop protection, seeds, nutrition products, agronomic solutions, and digital services that help farmers grow food responsibly and protect the environment. The CPR Chemistry team in Stein is at the forefront of this work, contributing to sustainable solutions that advance global food security. Syngenta has earned recognition as a top employer by Science Magazine and holds a Friendly Work Space label for all Swiss sites, reflecting a commitment to a supportive, inclusive culture. The Stein site offers access to advanced facilities and technologies, a collaborative environment, and opportunities to interact with a broad network of scientists within a strong regional science hub.

Mornings in the Stein lab

In this role you will lead and contribute to research programs that apply advanced chemistry and design to identify new bioactive ingredients and how they interact with biological targets important for crop protection. You’ll work with multidisciplinary project teams, both locally and globally, to push programs toward sustainable crop protection solutions. You’ll help move projects forward by applying expertise in molecular design, synthetic chemistry, and the practical problem solving that underpins efficient discovery. You will formulate hypotheses grounded in data, interpret complex structure–activity relationships by blending empirical results with predictive insight, and steer optimization across several properties to hit key project milestones. You’ll also champion the adoption of digital tools and data-driven methods within discovery workflows to speed up decision-making and keep science ahead of the curve.

Must-have capabilities for this role

• PhD in Organic Chemistry or Medicinal Chemistry, with postdoctoral or industry experience considered a plus
• Deep background in synthetic organic chemistry, with direct relevance to bioactive small molecules
• Strong ability to guide cross-functional teams and deliver project milestones within a complex matrix
• Self-driven, curious mindset with a willingness to adopt new technological approaches
• Clear English communication skills and proven talent for explaining complex science to diverse audiences

Nice-to-have attributes that help you stand out

• Interest in life sciences spanning small molecules and emerging chemical modalities
• Enthusiasm for deploying digital technologies in discovery and data analysis
• Creativity paired with solid decision-making and a commitment to continuous learning
• Strong organizational abilities and time management
• Collaborative spirit with the capacity to build productive relationships across teams and geographies
• Dedication to fostering a diverse, inclusive and open work environment

Pay, benefits and practical details

The role benefits from state-of-the-art research facilities and technologies that support agrochemical design, synthetic organic chemistry, and active ingredient optimization. The company cultivates an open, flexible workplace culture and emphasizes a digitally enhanced R&D process, giving you chances to grow digital data analysis skills and participate in multidisciplinary training programs. There is a robust network within the regional science hub that helps scientists connect, share knowledge, and expand professional contacts. Career development is a focus, with a multidisciplinary training program designed to advance a rewarding path in crop protection. The Stein site also offers a competitive pension fund plan, an attractive bonus system, onsite doctor, fitness room, canteen, and family-friendly initiatives including child and family allowances.

Advice for applicants from a recruiter’s desk

Lead your resume with your PhD specialty in Organic or Medicinal Chemistry and highlight hands-on experience in synthesizing bioactive small molecules, plus any leadership of cross-disciplinary projects.

Demonstrate the must-have skills with concrete examples: show how you have steered multidisciplinary teams, met project milestones, and used molecular design and SAR analysis to drive optimization, including any use of digital or AI-enabled workflows.

Prepare for interviews by outlining how you approach designing and testing new crop protection compounds, how you communicate findings to both technical and non-technical audiences, and how you handle data-driven decisions in a collaborative setting.

Ask a thoughtful question about how the CPR Chemistry team currently integrates digital tools and AI into discovery workflows or how the regional science hub supports ongoing collaboration with other life-sciences researchers.

How to apply for this Stein role

To apply, please submit your complete application with a CV written in English, along with your diploma and any work certificates (if applicable).