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Senior Scientist - Oligo Bioinformatics

Merck Group
Full-time
On-site
Billerica, MA
$111,100 - $166,600 USD yearly

JobsCloseBy Editorial Insights

EMD Serono in Billerica, MA is seeking a Senior Scientist: Oligo Bioinformatics to join the Oligonucleotide Therapeutics Group. You will design and run pipelines mapping oligos to genomes and transcriptomes, process data, deploy Dockerized apps, and contribute to siRNA, ASO and SSO therapeutics development. Requirements include a PhD with 3+ years of relevant experience, strong UNIX skills, and Python or R; hands-on NGS experience with tools such as Samtools, GATK, Bowtie/HISAT2, STAR, Salmon, DESeq, plus Illumina data and ideally PacBio or Nanopore. Preferred: Docker and Nextflow, Shiny/Streamlit apps, MySQL. Tips: tailor your resume to show end-to-end pipelines, provide links to apps or code, and clearly demonstrate impact. Onsite, full-time; pay 111,100 to 166,600; sponsorship not offered.


 

Work Your Magic with us! Start your next chapter and join EMD Serono.

 

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.  

 

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

 

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US. 

 

Your Role:

EMD Serono in Billerica, MA is seeking a Senior Scientist – Oligo Bioinformatics to add to their Oligonucleotide Therapeutics Group (DDTech).

Responsibilities:

  • Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes
  • Design and build pipelines that process and analyze related data, store summary results and integrate with the corporate ELN
  • Develop pipelines that determine mapping coordinates and homology of oligonucleotides to genomes and transcriptomes
  • Develop, deploy, manage, and run applications using Docker containers
  • Discovery and development of oligonucleotide therapeutics

 

Who You Are: 

Minimum Qualifications:

  • PhD in Chemistry, Chemical Engineering, Computer Science or other Science field with 3+ years of direct experience in siRNA/ASO/SSO

 

Preferred Qualifications:

  • Experience with common human genetics resources and techniques
  • Deployment of interactive applications from scripting languages like R and Python (Shiny and streamlit)
  • Experience with relational databases; hands on experience with MySQL
  • Experience in common NGS analyses task such mapping reads, quantification of gene expression, and/or variant calling
  • Experience with common bioinformatics tools like Samtools, GATK, Bowtie, HISAT2, BLAST, htseq-count, DESeq, Salmon, STAR, or Subread
  • Knowledge of Illumina sequencing data analysis is necessary and experience with PacBio and/or Nanopore sequencing
  • Familiarity with UNIX computing environment and proficiency in either Python or R scripting
  • Experience with docker and Nextflow pipeline
  • Ability to communicate finding of NGS data to a general scientific audience in both oral and written forms

 

Pay Range for this position: $111,100 - $166,600

 

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here

 

 

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

 

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!